Overuse of antibiotics can lead to drug-resistant bacteria that have to be treated with more powerful and often more expensive drugs.

过度使用抗生素会导致耐药菌，而这些细菌要得到治愈就必须使用药效更强大，通常也更昂贵的药物。

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Q: Mycobacterium tuberculosis is becoming resistant to more and more drugs, cheap diagnosis leaves much to be desired, and the BCG vaccine has varying efficacy and is 80 years old.

问：结核分枝杆菌现在对越来越多的药物产生抗药性，廉价的诊断方法有太多不尽如人意的地方，而卡介苗疫苗的疗效不尽相同，使用至今已有80年之久。

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The disease has proven to be resistant to chemotherapy and other drugs, and in the past 20 years, only two treatments have been widely approved, with many other drugs failing in Phase III trials.

这种疾病已经被证明对化疗和其他一些药物治疗有抗药性，在过去20年中只有两种药物被批准应用于胰腺癌的治疗，其他很多药物都倒在了三期临床试验上。

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Panic attacks had just been defined as a diagnosis and were assumed to be resistant to Valium-like drugs.

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