Objective: To explore the relationship between CAG microsatellite polymorphism of androgen receptor gene and hyperandrogenism of polycystic ovary syndrome (PCOS).
目的探讨雄激素受体基因微卫星CAG多态性与多囊卵巢综合征(PCOS)患者高雄激素血症的关系。
Conclusion: androgen receptor gene CAG microsatellite polymorphism exists in Chinese women does not significantly relate with pathogenesis of hyperandrogenism and is not the main cause of PCOS.
结论中国汉族雄激素受体基因微卫星CAG多态性对PCOS高雄激素血症的形成无明显关系,不是PCOS的主要致病因素。
Conclusions Androgen receptor gene CAG length showed polymorphism in older men, most of the CAG length focused on 21-24. This study offered the basic data on relationship for AR gene and disease.
结论自然人群中老年男性雄激素受体基因CAG重复序列呈现多态性,多数集中在21 - 24,为进一步研究AR基因变异与疾病的关系提供依据。
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