...合成;抗惊活性;构效关系[gap=839]Key words 4-substituted amino-6-phenylpyrimidine;synthes is;anticonvulsant activity;structure-activity relationships ...
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RESULTS: 6 compounds showed anticonvulsant activity.
结果:有6个化合物具有抗惊厥活性。
Levetiracetam is an antiepileptic drug with novel antiepileptic mechanism, in which binding to SV2A, a synaptic vesicle protein, may result in its anticonvulsant activity.
左乙拉西坦是一种新型作用机制的抗癫癎药物,其抗癎机制可能是通过影响突触囊泡蛋白SV2A来实现。
Objective To study if calmodulin antagonist has anticonvulsant activity, and to provide theoretical evidence for exploring new anticonvulsant drug to improve clinical epilepsy therapy.
目的了解钙调素拮抗剂有无抗痫作用,为临床上开发新型的抗痫药以进一步控制癫痫提供理论依据。
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