Antisensepeptidesare defined as the sequense of amino acids encoded in the antisense strand of DNA and read in either the 5 to 3or 3 to 5 direction respectively.
The terms sense and antisense were coined by Paul Zamecnik to show the complementary, double-strand nature of DNA. One strand consisted of alternating patterns of the four nucleotides that make up DNA adenine, cytosine, guanine and thymine and it could be read in order.