轴索变性(axonal degeneration) 神经元病( 神经元病(neuronopathy):神经元胞体变性坏死, 短时间内继发轴索全长变性&髓鞘破坏.
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Acute SCI generally leads to axonal degeneration, neuronal necrosis, glial scar, etc. , and causes limb paralysis and paraplegina.
急性脊髓损伤主要导致轴突变性、神经元坏死、胶质瘢痕生成等,从而造成肢体麻痹、截瘫。
参考来源 - 大鼠急性脊髓损伤修复相关难溶蛋白的谱系研究Necrosis of arteries around the epineurium,the inter-wall infiltration of inflammatory cells and axonal degeneration is the specific features of vasculitis peripheral neuropathy.
2.周围神经外膜小动脉坏死、跨壁炎细胞浸润、有髓纤维轴索变性,为血管炎性周围神经病特异性病理表现。
参考来源 - 血管炎性周围神经病临床与病理研究·2,447,543篇论文数据,部分数据来源于NoteExpress
The abnormality of neurofilaments(NF) plays a possible role in axonal degeneration of Alzheimer's Disease(AD), but the mechanism remains unclarified.
阿尔茨海默病(AD)患者脑中神经细丝异常可能在其轴突退化中起重要作用,但机制不明。
Conclusion: Local high concentration of DMSO can delay axonal degeneration, which indicates that DMSO can be used for adjuvant treatment of neurodegenerative diseases.
结论:局部高浓度的DMSO能够延缓轴突的退行性病变,提示DMSO可能用于神经退行性疾病的辅助治疗。
The above changes in disconnected group were similar to those in positive control group. No obvious protective effects on axonal degeneration were observed in blank and DMSO control groups.
这种变化与阳性对照组非常相似,而空白对照组和DMSO对照组未见明显保护轴突退行性病变的作用。
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