At the very least, you might be irritated with rules or have a sense of confinement.

至少，你可能对规定很恼火，或者有种被限制的感觉。

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Then you should not be irritated, Mary, because the dog does not know it is wrong to play with your toy.

那么玛丽，你不应该生气，因为狗不知道玩你的玩具是不对的。

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The mental health of humans in space has been extensively studied. Depression can set in, people become irritated with each other, and sleep can be disrupted, studies have found.

人类在太空的精神健康一直得到广泛的研究。研究发现，人们可能出现抑郁症状，彼此发火，睡眠也可能受到影响。

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If they end up with the penalty, they may be less irritated since they consciously decided to take the risk, he said.

WSJ: Packages of Perks Present New Bundle Jungle for Air Travelers

This might be down to the fact that users are increasingly becoming irritated by the number of advertisements and the file quality available with such services, said Jupiter Media analyst Dan Stevenson.

BBC: Music swapping on the net rising