...产生腹痛, 水电解质紊乱等不良反应,长期使用可丧失蛋白质而 软弱无力,因损害直肠肌间神经丛而形成导泻的结肠(cathartic colon),此类制剂含有 蒽醌,长期摄取后在结肠黏膜下有黑色素沉积,形成所谓的 结肠黑变病,为一种良性和可恢复的病变。
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Results The frequency and amplitude of slow wave in vivo of rats with cathartic colon was decreased markedly.
结果“泻剂结肠”大鼠的结肠慢波频率减慢,振幅降低;
Methods the model of rat with "cathartic colon" was established, and the changes of colonic electromyography of the rat was examined.
方法建立大鼠“泻剂结肠”模型,并测定其结肠的肌电生理活动变化。
Methods: Set up mouse model of cathartic colon, and measure intestine transmission function by detecting activated charcoal moving in the intestine.
方法:采用大鼠泻剂结肠模型,采用活性炭悬液推进法测定肠道传输功能。
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