直接法包括手性固定相(chiral stationary phase,CSP)法和手性流动相添加剂(chiral mobile Phase additives,CMPA)法,前者将手性选择物固定 在HPLC担体上,使用填充CSP的专门的手性色谱 柱实现对映体的分离,后者...
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In additional the influence of the mobile phase composition , pH% the mobile flow-rate , the concentration of chiral mobile phase additive on the separation factor are studied.
考察了流动相的组成、pH值、流速以及手性流动相添加剂的浓度对拆分选择性的影响。
参考来源 - 高效液相色谱手性流动相添加剂法拆分药物对映体The chiral separations of Mannich enantiomers were studied by using Vancomycin (Chirobiotic V) and Cellulose (Sumichiral OA 2500s) Chiral Stationary Phase (CSP), Chiral Mobile Phase Additive (CMPA) and Chiral Ligand-Exchange Chromatography (CLEC) in this study.
本文研究了应用大环抗生素类万古霉素手性固定相(Chirobiotic V)法和纤维素类手性固定相(Sumichiral OA 2500s)法,手性流动相添加剂法和手性配体交换色谱法分离曼尼希碱类活性化合物对映异构体。
参考来源 - 几个曼尼希碱化合物对映异构体的HPLC手性分离分析研究·2,447,543篇论文数据,部分数据来源于NoteExpress
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