Objective To investigate the effect of Bai-song tablet on 5-hydroxytryptamine (5-HT) and dopamine (DA) in hippocampus of experimental chronic unpredictable stress rats.
目的观察中药白松片对慢性应激大鼠海马5-羟色胺(5-HT)和多巴胺(DA)含量的影响。
Conclusion It is an ideal method for establishing the animal model of post-encephalorrhagia depression to give chronic unpredictable mild stress to rats on the basis of cerebral hemorrhage.
结论在脑出血的基础上给予慢性不可预见的温和应激,能建立较理想的脑出血后抑郁动物模型。
METHODS: (1) The chronic stressed depression rats were established by chronic unpredictable mild stress and separation after 21 days.
方法:(1) 动物模型:连续21天慢性轻度不可预见性应激配合孤养方法建立大鼠抑郁模型。
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