How sad that all his hard work should come to nothing.

他的所有辛勤劳动竟全部付诸东流，太让人伤心了。

《牛津词典》

Their meeting had come to nothing.

他们之间的会见毫无结果。

youdao

It seemed that mom's dream of having a boy had come to nothing.

看样子妈妈生一个小弟弟的梦想是破灭了。

youdao

If it passed directly through the tube and nothing happened to it, it would come out to the outside world again.

如果它直接穿肠而过,中间没有任何事情发生,它又会回到外面去

耶鲁公开课 - 生物医学工程探索课程节选

There are other people who come to these classes ; who grew up in a non-religious context; they know nothing about this.

还有一些来上这门课的人,无任何宗教背景;,对此也一无所知。

耶鲁公开课 - 新约课程节选

It's OK to use certain fundamental constants that come in a lot of calculators, so there's nothing we can do about that. That's OK.

当然允许使用,一些普通计算器里都有的基本常数，我们不会连这些都不让用，这是没问题的。

麻省理工公开课 - 化学原理课程节选

Unite has warned that industrial action is a possibility, if negotiations with management come to nothing.

BBC: Aberdeen bus drivers consider next move over pay row

The Labour leader said on jobs, growth and inflation, Mr Osborne's promises had come to nothing.

BBC: Ed Miliband: Cuts plan has locked UK into vicious cycle

He says he knows that many if not most of his foundation's projects will fail or come to nothing.

WSJ: The New Science Behind Philanthropy | WSJ.Money Summer 2013