高血糖引起的糖基化终末产物形成,从而导致一系列细胞因子产生,如结缔组织生长因子(connective tissue growth factor CTGF),转化生长因子-β(TGF- β),由这些细胞因子促进肝脏的纤维化。
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Objective to investigate the expression of connective tissue growth factor (CTGF) in the kidney of STZ induced diabetic rats and its relationship with the early renal hypertrophy.
目的:研究结缔组织生长因子(CTGF)在链脲佐菌素(STZ)诱导的糖尿病大鼠肾脏中的表达及其与肾小球肥大的关系。
Objective to observe the effects of antisense RNA of connective tissue growth factor (CTGF) on rat liver fibrosis.
目的观察结缔组织生长因子(CTGF)反义rna对实验性肝纤维化的影响。
ObjectiveTo investigate the effect of somatostatin analogue-octreotide (oct) on expression of connective tissue growth factor (CTGF) gene of murine hepatic stellate cells (HSCs) in vitro.
目的研究生长抑素类似物奥曲肽(oct)对体外培养的大鼠肝星状细胞(HSC)中结缔组织生长因子(CTGF)基因表达的影响。
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