spinal cord injury 脊髓损伤 ; 脊椎损伤 ; 脊髓受伤 ; 脊柱损伤 contusion of spinal cord 脊髓挫伤 spinal cord compression 脊髓压迫 ; 压迫 ; 脊髓受压迫 ; 脊髓受压 ..
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Objective To investigate the neuroprotective effect of heat shock response induced by FK506 on spinal cord contusion in rats.
目的:探讨FK506诱导热休克反应对大鼠脊髓冲击伤的神经保护作用。
CONCLUSION: the rat model for controlled spinal cord contusion injury is reproducible and suitable for the pharmacodynamic screening of neuroprotective drugs.
结论:建立的控制性脊髓挫伤大鼠模型重复性好,适合神经保护药物的药效学筛选。
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