【Key words】 liposomes； solubilization； cosolvent systems； monophase solutions； freeze-drying；
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The solute solubility in cosolvent systems has also been estimated using a Ig - linear solubility model and UNIFAC method. The calculated results were in good agreement with the experimental values.
利用对数线性模型，以及UN IFAC基团贡献法对溶质的溶解度进行了估算，发现估算值与测定值吻合得较好。
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