Objective To observe behavioral changes and the dynamic expression of cyclooxygenase-1(COX-1) in the spinal cord of rats after unilateral sciatic cryoneurolysis(SCN).

目的观察大鼠坐骨神经冷冻（SCN）后行为学变化以及脊髓环氧化酶-1（COX-1）的表达。

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Aim To observe the expression of cyclooxygenase COX-1 and 2 in brain after spared nerve injury (SNI).

目的观察坐骨神经损伤(SNI)后小鼠脑环氧合酶cox - 1和2的表达变化。

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To observe the expression of cyclooxygenase (COX) -1 and COX-2 in brain after spared nerve injury (SNI) and compare the analgesic effects of COX inhibitors with different selectivity.

为了观察坐骨神经损伤(SNI)后小鼠全脑环氧合酶(COX) - 1和COX - 2的表达变化，以及不同选择性的COX抑制剂对SNI所致神经病理性痛的效应。

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Needleman's theory was that one could spare the stomach by selectively blocking the enzyme responsible for inflammation, COX-2 (cyclooxygenase-2), while avoiding the one involved in maintaining the stomach lining, COX-1.

FORBES: The Chemical Cobbler