Objective To investigate the association of cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) gene A/G polymorphism with susceptibility to diabetes mellitus in Han Chinese.

目的探讨细胞毒T细胞相关抗原4 （CTLA 4 ）基因A/G多态性与汉族人糖尿病易感性的关系。

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Both drugs turn off a natural brake on immune system activity called CTLA4 (cytotoxic T-lymphocyte antigen 4).

FORBES: Magazine Article

Pfizer's drug tremelimumab and Bristol-Myers Squibb's ipilimumab are antibodies to a protein called CTLA-4 (cytotoxic T-lymphocyte antigen-4) that acts as an emergency brake to prevent killer T cells from attacking healthy tissue.

FORBES: Targeting Melanoma