The extreme difficulty in tracing the manufacturing and distribution channels of counterfeit medicines makes their circulation on markets difficult to stop.

由于在追查制造假冒药品及其分销渠道上困难重重，因而难以阻止假冒药品在市场上的流通。

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The extreme difficulty in tracing the manufacturing and distribution channels of SFFC medicines makes their circulation on markets difficult to stop.

由于在追查制造假冒药品及其分销渠道上困难重重，因而难以阻止假冒药品在市场上的流通。

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I had ever seen mother cried in such way, even in extreme difficult days, mother still retained the image of fortitude.

我从没见母亲这样哭过，即使是在异常艰难的日子里，母亲的形象也是坚毅的。

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And that the bond market will crack at some point, though putting a date on that is very difficult given extreme government intervention in the market.

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But Roy Miller said that she had not received so definitive a diagnosis, and that, in any case, it could be difficult to sustain in court the notion that Amy was beset by extreme delusions.

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In particular, the extreme mobility of modern financial capital makes monetary policy more difficult to conduct.

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