That makes it far more difficult to manipulate a woman than a man.

这使得处理女人的问题要比处理男人的问题难得多。

youdao

Improperly implemented, dials can be extremely difficult to manipulate.

如果设计不当，刻度盘将会非常难于操作。

youdao

Unfortunately, they are also typically quite frustrating, difficult to manipulate, and wasteful of pixels.

遗憾，它通常也 很 令人沮丧，难于操作，而且浪费像素。

youdao

During their test drive, the team at Trusted Reviews found the device to work quite well -- mostly due to its 2, 000dpi laser sensor -- although they thought that the top-mounted buttons were somewhat difficult to access, and joystick mode can't be used to manipulate the Z-axis.

ENGADGET: Fanatec Head$h0t gaming mouse reviewed