...与健康研究中心博士后研究员) 校对者：李文宗 (台大流行病学研究所教授) 近年来疾病易感受性基因 (disease susceptibility gene) 研究盛行，研究者利用病例对照研究法 (case-control study) 进行基因相关研究时，若忽略研究母群可能潜藏的 ..
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The goal of this unit is to introduce gene-gene interactions (epistasis) as a significant complicating factor in the search for disease susceptibility genes.
这一单元的目的是介绍基因-基因相互作用(上位性)作为疾病易患基因研究中的一个显著的并发因素。
It is now known that genetic variability accounts for 25% of susceptibility to the disease, but that variations in the sickle-cell gene contribute to only a fraction of that.
现在，25 %的对疾病的敏感性被归咎于遗传变异。但在镰细胞基因上的变异仅仅参与了其中的一小部分。
Conclusions These results may provide clues to reveal the susceptibility gene of vitiligo in China and as well as the immunogenetic mechanisms of the disease.
结论该结果为进一步揭示白癜风的易感基因及免疫遗传发病机制提供了线索。
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