Conclusion The combined use of RSG and CDDP can induce apoptosis of A549 cells and it shows evidently time and dose dependence.

结论罗格列酮与顺铂合用能诱导肺癌A549细胞调亡，呈明显的时间及剂量依赖性。

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The rate of the apoptotic cells of RA was significantly higher than those of OA ( P< 0.01) and NC ( P< 0.01). There was dependence of time and dose within a certain range.

RA组凋亡细胞百分率显著高于OA组（P＜0．01）和正常对照组（P＜0．01），在一定剂量范围内具有时间和浓度依赖性。

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Objective To study time and dose dependence of animal models with brain neoplasms induced transplacentally with N-ethyl-N-nitrosourea (NEU).

目的探讨亚硝基乙基脲（NEU）经胎盘诱发脑肿瘤动物模型的时间和剂量依赖性。

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