Their utility is limited by cost, and potential dose-dependent risks, such as local inflammatory reactions and ectopic bone formation.
但是它的实用性受到价格和潜在的剂量依赖的风险像局部的炎症反应和异位骨形成限制。
It is suggested that high dose aluminium can affect in rats bone matrix gelatin-induced ectopic bone formation and hinder its mineralization, giving rise to osteomalacia.
提示高剂量铝可影响大鼠骨基质明胶诱导性异位骨形成，阻碍其矿化作用，引起骨软化。
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