Thiscancer starts in the cells that line the esophagus (thetube that carriesfoodfrom thethroatto the stomach) and usuallyoccursinthe lowerpartoftheesophagus, according to the MayoClinic.
Doctors can sometimes see the cancer coming years earlier when acid reflux causes cells in the esophagus to mutate to become more like stomach tissue, a condition called Barrett's esophagus.