... 指导思想guiding ideology 具有重大和深远的意义far-reaching and profound significance 以最大的努力exert our upmost efforts ...
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The joint statement has extraordinary significance as well as a profound and far-reaching impact as it lays down new navigation marks for the advancement of China-US relations.
联合声明为中美两国关系前行设立了新航标，意义非凡、影响深远。
It has far-reaching significance both for theory and practice to have a profound study of the railway tunnel deformation failure characteristics.
所以进一步开展铁路隧道变形特征研究具有一定的理论意义和重要应用价值。
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