【frame-shift_mutation】什么意思_英语frame-shift_mutation的翻译_音标_读音_用法_例句_在线翻译

frame shift mutation

[遗] 移码突变

... fetal alcohol syndrome胎儿酒精综合征 frame-shift mutation移码突变 functional cloning功能克隆 ...

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帧转移突变

one of the factors leadingto good health » 的因素之一leadingto健康状况良好 Frame-shift mutation » 帧转移突变 consideration set » 考虑设置 ..

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医药科学 | 生物学

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abstract: A frameshift mutation (also called a framing error or a reading frame shift) is a genetic mutation caused by indels (insertions or deletions) of a number of nucleotides in a DNA sequence that is not divisible by three. Due to the triplet nature of gene expression by codons, the insertion or deletion can change the reading frame (the grouping of the codons), resulting in a completely different translation from the original.

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Conclusions No functional FANCA protein was found in these 3 cases of FA-A, and intragenic deletion, frame shift and splice site mutation were the major pathogenic mutations found in FANCA gene.

结论3例FA-A型患者均无功能性FANCA蛋白表达；基因缺失、移码突变和剪切位点突变是FANCA基因的主要失活方式。

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