傅-克酰基化反应(Friedel-Crafts acylation)的反应机制和烷基化是类似的,也是在催化剂的作用下,首先生成酰基正离子,然后和芳环发生亲电取代。
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有机英语整理 ... Oxidation of Alkene and Alkyne 烯烃和炔烃的制备 Friedel-Crafts Acylation 付——克酰基化 Claisen 重排反应 ...
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Chrysophanic acid in total yield of 40.4% was synthesized from 3-nitrophthalic acid by dehydration, friedel-crafts acylation, reduction, diazotization, hydrolysis and cyclization.
以3-硝基邻苯二甲酸为起始原料,经付克酰化反应、还原、重氮化、水解、环合合成了大黄酚。
参考来源 - 大黄酚和大黄酸合成实验室工艺研究·2,447,543篇论文数据,部分数据来源于NoteExpress
An improved and optimum process for preparing 2-Amylanthraquinone by re-acting t-amylbenzene with phthalic anhydride, involving Friedel-Crafts acylation (yield 80. 2%) and cyclization(yield 81.4%).
以叔戊苯和笨酐为原料,通过酰基化和关环合成了2—戊基蒽醌,改进和优化了各步合成工艺条件,酰化收率80.2%,关环产品收率81.4%。
Methods and results:Through acylation, Friedel Crafts reaction, reduction, hydrolysis, condensation and oxidation, the title compound was prepared with a total yield of 50.7%.
方法:以庚二酸单乙酯为原料,经酰氯化、傅克酰化、还原、水解、缩合及氧化反应合成塞曲司特。 结果:塞曲司特的总产率为5 0 .7%。
METHODS: The title compounds were synthesized by acylation of twelve acyl chlorides and two intermediates prepared by Friedel Crafts reaction, lengthening of carbon chain, hydrolysis and cyclization;
方法:通过付克反应、碳链延长、水解和环合反应得到两个关键中间体,然后通过酰化反应制得各种酰胺化合物;
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