糖稳态的神经免疫内分泌调控轴及药物干预研究进展 - 中国新药杂志 关键词: 神经内分泌免疫调节网络;调控轴;糖稳态 [gap=680]Key words: neuroendocrine immune-modulation network; axis; glucose homeostasis
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BACKGROUND AND OBJECTIVEGhrelin as the endogenous ligand of the growth hormone secretagogue receptor was found to play a role in the regulation of energy balance and glucose homeostasis,it had been connected to type 2 diabetes mellitus (T2DM) intimately.
背景与目的生长激素促分泌剂受体内源性配体ghrelin在调节人体能量和糖代谢平衡方面具有一定作用,与2型糖尿病(T2DM)关系密切。
参考来源 - Ghrelin与2型糖尿病心脑血管并发症的关系·2,447,543篇论文数据,部分数据来源于NoteExpress
The role of the central nervous system in glucose homeostasis also has been well established.
在葡萄糖稳态中存在着中枢神经系统调节。
Moreover, decreasing LPL activity in adipose tissue and preventing excess lipids accumulation in tissues may contribute to the ability of FSH to maintain lipid and glucose homeostasis.
此外,FSH能降低脂肪组织LPL活性,减少脂质在组织中的积累,也可能是FSH维持糖、脂代谢稳定的一个重要原因。
As NRs play major roles in the regulation of lipid metabolism, glucose homeostasis, and inflammatory processes, they are considered as ideal targets for the treatment of cardiovascular diseases.
由于核受体在调节脂质代谢、糖代谢以及炎症反应方面发挥重要作用,它们是治疗心血管疾病理想的靶标。
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