The two have nothing in common.

两者毫无相同之处。

《新英汉大辞典》

Two entirely separate islands, or worlds, might have different languages, and most likely have nothing in common.

两个完全相隔的岛或者世界之间，会有不同的语言，并且很有可能毫无相通之处。

youdao

When I look at my brother I see someone I have nothing in common with: he sees a half-assed writer who CARES only for esoteric matters.

当我看着弟弟时，我看到一个和我没有任何共同点的人：他看到的是一个不着调的作家，关心的都是些深奥的东西。

youdao

For her the idea that birds have come from dinosaurs is just common knowledge and there's nothing surprising in that at all."

VOA: special.2009.12.01

It seemed to have nothing in common with asthma, arthritis and other diseases of inflammation.

FORBES: Prevention Puzzle

At the time, the fields seemed to have nothing in common except the hallways of Building 20.

NEWYORKER: Groupthink

At first look, The Behavior Gap and Gents with No Cents appear to have nothing in common.

FORBES: A Couple of Interesting Short Books