Objective To study the clinic features and the mechanism of skin damage induced by high-dose methotrexate (HD-MTX).
目的了解大剂量氨甲蝶呤(HD - MTX)化疗引起皮肤损伤的临床特征,并探讨其发生机制。
Objective To discuss the practicability of high-dose methotrexate (HD-MTX) in treatment of acute lymphoblastic leukemia (ALL) in children in basic-level hospitals.
目的探讨大剂量甲氨蝶呤(HD - MTX)治疗急性淋巴细胞白血病(all)在基层医院的可行性。
OBJECTIVE: to improve the efficacy and safety of high dose methotrexate (HDMTX) chemotherapy in the treatment of children with acute lymphoblastic leukemia through blood concentration monitoring.
目的:通过血药浓度监测,提高对小儿急性淋巴细胞白血病大剂量甲氨蝶呤化疗的有效性和安全性。
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