...摘要 ： 表遗传修饰和染色质结构重组（chromatin remodelling）参与了胚胎形成及肿瘤发生，组蛋白乙酰化（histone acetylation）是调控基因转录的关键因素之一。组蛋白去乙.
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histone acetylation modification 组蛋白乙酰化修饰
histone acetylation and deacetylation 组蛋白乙酰化和去乙酰化
acetylation of histone 组蛋白乙酰化
acetylation of core histone 核心组蛋白的乙酰化
Histone acetylation contributes to expression of gene, while histone deacetylation leads to repression of gene expression.
组蛋白乙酰化促进基因表达，而去乙酰化则抑制基因表达。
Histone acetylation and deacetylation can regulate many chromosome functions, such as gene expression and chromosome segregation.
组蛋白乙酰化和去乙酰化可调节染色体的多种功能，例如基因表达和染色体分离等。
As in the Alzheimer's mice, drugs that boosted histone acetylation improved the older mice's performance on tests of rodent cognition.
如同阿尔茨海默病鼠，增强组蛋白乙酰化的药物改善了年老小鼠在认知测试中的表现。
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