...关键词： 组蛋白甲基化修饰；组蛋白甲基转移酶；抗肿瘤药物；表观遗传 [gap=778]Key words： histone methylation modification; histone methyltransferases (HMTs); anti-cancer drug; epigenetics ..
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Core processes of epigenetic inheritance include DNA methylation, histone modification, nucleosome remodeling, nuclear dynamics and chromatin interaction with non-coding RNAs.
核心过程的表观遗传的产业包括DNA甲基化、组蛋白改性、核小体重建、核染色质动力学和互动子都存在。
Epigenetic mechanisms, including DNA methylation, histone modification and chromatin remodeling, have been demonstrated to be involved in the development of SLE.
表观遗传学涉及的机制主要包括DNA甲基化和组蛋白修饰及染色质重塑。
DNA methylation catalyzed by DNA methyltransferases interacts with histone modification to inhibit gene transcription, induce gene silencing at the participation of many regulators.
DNA甲基化由DNA甲基转移酶催化，在多种调节因子的参与下，与组蛋白修饰相互作用，抑制基因转录，导致基因沉默。
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