Objective: To rationally design new inhibitors of HIV-1 integrase.
目的：合理设计新的HIV-1整合酶抑制剂。
Because of the special function of HIV-1 integrase, it has become one of focuses of anti-AIDS drug design.
由于HIV - 1整合酶的特殊功能，它已成为抗艾滋病药物设计工作的焦点之一。
Aim To synthesize a series of new caffeic acid derivatives and test their HIV-1 integrase inhibitory activities.
目的合成新型咖啡酸衍生物并测定其抑制HIV 1整合酶活性。
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