Hypoxia activates hypoxia-inducible factor 1 (HIF-1), thus it controls a series of expression of genes correlated with hypoxia.
低氧可激活低氧诱导因子(HIF - 1),从而调控一系列与缺氧相关基因的表达。
Hypoxia inducible factor-1 (HIF-1) is a key oxygen-dependent transcription factor that up-regulates many protective genes against hypoxia-induced injury.
低氧诱导因子1 (HIF - 1)是重要的氧依赖性核转录因子,低氧条件下能上调多个靶基因表达以减少缺氧性损伤。
Hypoxia-inducible factor-1(HIF-1), a newly discovered factor in recent years, is an important transcription factor which can control the cells′adaptive responses to hypoxia.
缺氧诱导因子1(HIF-1)是近年发现的调控细胞低氧适应性变化的重要转录因子。
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