Activation of this process in immature T cell by the bindng of the TCR CD3 to self antigens may therefor be the mechanism which produces clonal deletion and consequently self tolerance.
未成熟T 细胞通过TCR-CD3 复合物与自身抗原接合激活上述过程可能与克隆清除的形成机制及自我耐受有关。
JM is a acute lymphocytic leukemia cell line derived from immature t lymphocytes in human thymus.
JM是来自人胸腺不成熟t细胞的急性淋巴细胞白血病细胞系。
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