Prader-Willi syndrome (PWS) is an example genetic disorder due to a loss of paternal imprinted gene expression in the 15q11-q13.
PWS是一种由于15q11-q13区域父源性印记基因表达缺陷引起的遗传性疾病。
参考来源 - 眼皮肤白化病Ⅰ型和PraderAccumulating evidence suggests that deregulation of imprinted gene, including loss of imprinting (LOI) that is the biallelic expression of the imprinted gene, plays a role in oncogenesis.
越来越多的研究表明印迹基因的反常包括印迹丢失(loss of imprinting,LOI)即双等位基因表达,在肿瘤的发生中起着一定作用。
参考来源 - 印迹基因H19、LIT1和MEST在肺癌发生中的作用机制研究·2,447,543篇论文数据，部分数据来源于NoteExpress
Recently researchers find that a new tumor suppressor imprinted gene ARHI(NOEY2)is involved in the onset and progression of cancer.
近年来研究表明，一种新的抑癌印迹基因ARHI（NOEY2）的异常参与了一些肿瘤的发生。
Plants use these epigenetic silencing mechanisms extensively to control development and parent-of-origin imprinted gene expression.
植物广泛地使用这些表观沉默机制来控制发育及亲本来源的印记基因表达。
Part I Expression of PEGS in GliomasPEG3 (Paternally Expressed Gene 5) is an imprinted gene of which only the paternal allele is expressed.
父性表达基因3）是一个印迹基因，只有来源于父方的等位基因才表达。
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