Humor has a positive psychological effect when we are in difficulties.

当我们遇到困难时，幽默会对我们的心理产生积极的影响。

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Remember next time don’t trust the advice of a man in difficulties.

处于困境之中的人为了摆脱困境，往往不惜牺牲别人的利益，所以他们的建议常常是不可信的。

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The company is in difficulties at the moment, but we expect it to do well in the long run.

这家公司目前处于困境，但是我们期望它终究会经营很好。

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Still,with all these difficulties, ten-thousand troops made it to Washington in the first few weeks of the Civil War.

VOA: special.2009.08.20

A lot of sciences rest on data that is flawed in some ways because of the difficulties in assessing what people eat.

许多依赖数据的科学常识是有瑕疵的,由于评估人类所吃食物非常困难

耶鲁公开课 - 关于食物的心理学、生物学和政治学课程节选

Do you have any difficulties in studying as a grad student?

你做为一个研究生学习有困难吗？

苦中有乐的学习 - SpeakingMax英语口语达人

The government will arrange counselling and other assistance to farmers who find themselves in difficulties.

BBC: NEWS | South Asia | Aid for Indian suicide families

They should avoid trying to drive or walk through any flooding as you could end up in difficulties.

BBC: Flooding closes railway and roads

North Wales Police who were called out to help stranded motorists in some cases found themselves in difficulties coping with the conditions.

BBC: Couple in car stuck in snow drift near Bala overnight