He lost all his money gambling and now he's really in Queer Street.

他把钱都输光了，现在可真狼狈了。

youdao

If you are one of those who rails against the short-termism and excessive risk-taking of some banks and finance businesses, you might note that a public sector financial institution, the Debt Management Office, has taken a reassuringly long-term approach to managing the UK government's debts - and without its prudence, we might all be in Queer Street or Skid Row by now.

BBC: Why investors love lending to the UK government