The study shows that the inactivation of gene Atp6v0d2 in mice results in dramatically increased bone mass due to defective osteoclasts as well as enhanced bone formation.
研究表明，小鼠Atp6v0d2基因的失活，导致骨量显著增加，其主要原因为破骨细胞功能缺失和骨形成增加。
DNA methylation may be an important mechanism of inactivation of RUNX3 gene in HCC.
甲基化机制可能是肝细胞癌runx3基因失活的重要机制之一。
The methylation of histone H3-K27 was proved to be linked to several silencing phenomena including homeotic-gene silencing, X inactivation and genomic imprinting.
组蛋白H3第27位赖氨酸的甲基化与同源盒基因沉默、X染色体失活、基因印记等基因沉默现象有关；
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