Two are "integrase inhibitors" that block the HIV genetic material from attaching to the host cell's DNA.

其中两种药物是“整合?抑制剂”，它可以阻止艾滋病病毒的遗传物质附加到宿主细胞的DNA中。

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Integrase inhibitors 2007 integrase inhibitors interfere with the integrase enzyme, which HIV needs to insert its genetic material into human cells.

整合酶抑制剂；首次获准：2007年；抗病毒方式：整合酶抑制剂干预了整合酶酵素，艾滋病病毒正是通过整合酶酵素将自己的遗传物质传到人类细胞。

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The application value of each representative system was evaluated to provide some guidance for the platform established for the drug design and screening of HIV-1 integrase inhibitors.

给出了各个代表性体系的应用价值。旨在对HIV - 1整合酶抑制剂药物设计及筛选平台的建立提供一定的参考。

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In 2000 Hazuda and her team published two landmark papers showing that integrase inhibitors could be made.

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GlaxoSmithKline and Merck have both attempted to develop integrase inhibitors, which inhibit the viral DNA from integrating with human DNA. But their drugs have failed in trials due to problems with toxicity and other issues.

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GlaxoSmithKline (nyse: GSK - news - people ) and Merck (nyse: MRK - news - people ) have both attempted to develop integrase inhibitors, which inhibit the viral DNA from integrating with human DNA. But their drugs have failed in trials due to problems with toxicity and other issues.

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