Ai is despondent and angry... and really, can you blame her?

爱是沮丧和愤怒…，真的，你能责怪她吗？

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The medical research discovery, gets angry, is despondent, is intense.

医学研究发现，发怒、抑郁、紧张。

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Although the main perceived threat varies by time and place—from climate change to economic recession—the general mood is a bit despondent.

尽管感觉到的主要威胁因时因地而不断变化——从气候变化到经济衰退——人们的普遍情绪还是有点沮丧；

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Bradamante is despondent, and Alcina is left to exult over her latest conquest.

NPR: Love And Lunacy: Vivaldi's 'Orlando Furioso'

But she remains despondent and is afraid to go back to her village.

CNN: ASIANOW - TIME Asia | Pedophile Playground

The result of all of this is that many Serbs are pretty despondent about the future.

ECONOMIST: The Balkans after Milosevic