五、 基因敲除 与敲进 基因敲除 (knock out of gene):利用基因打靶技术,用无功能的外源基因转入细胞与基因组中同源序列进行同源重组,把具有功能的同源序列置换出来,造成功能基因...
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The [researchers] knock out one gene per embryo.It will probably take hundreds [of embryos] to find the gene.
研究人员在每个胚胎中都只改变一个基因,大概要试上几百个才能找出来。
Recent PTP-1B gene knock-out studies and anti-sense oligonucleotide (ASO) treatment in mice have identified PTP-1B as a potential target for chemotherapy of diabetes and obesity.
小鼠ptp - 1b基因敲除及反义核苷酸治疗实验表明PT P - 1b是治疗糖尿病和肥胖症的潜在靶标。
That is because it is relatively easy in flies to knock out the function of a single gene and then attempt cloning with these cells, which will test whether that gene is important.
这是因为在苍蝇中相对比较容易敲除一个基因的功能,然后尝试克隆这些基因敲除了的细胞,并检测这个被敲除的基因是否重要。
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