... disease,PD)是世界第二大神经系统退行性疾病。PD的病理性特征是黑质致密部多巴胺能神经元进行性缺失,以及路易小体(Lewy bodies,LBs)的生成,但其致病机理至今尚不清楚。α-突触核蛋白(α-synuclein,α-syn)是路易小体的主要组成部分,是PD关键蛋白。
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dementia with Lewy bodies 路易体痴呆 ; 路易氏体失智 ; 和路易体痴呆
Lewy bodies dementia 和路易体痴呆
diffuse lewy bodies dementia 弥漫性路易小体病
N-PLURAL abnormal proteins that occur in the nerve cells of the cerebral cortex and the basal ganglia, causing Parkinson's disease and dementia 路易氏体
They report that minimal gradual memory declines were seen in the absence of tangles, while Lewy bodies and strokes doubled the rate of gradual memory loss.
他们报告微小逐渐的记忆力下降被发现存在纤维丛，当路易小体和中风将逐渐记忆力下降的速率加倍时。
AIM: To compare the clinical characters of patients with dementia with Lewy bodies or with progressive supranuclear palsy, and differentiate those from other kinds of Parkinson Plus.
目的：比较路易体痴呆及进行性核上性麻痹的临床特点，并与其他的帕金森叠加综合征相鉴别。
Conclusion: Fluctuating cognitive impairment patient with recurrent visual hallucinations and spontaneous motor features of Parkinsonism shall be high suspected to be dementia with Lewy bodies.
结论认知功能减退的患者出现波动性认知功能障碍、反复的视幻觉和帕金森样运动障碍应高度怀疑路易体痴呆。
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