Their lively discussions spurred Maura to make small but nevertheless life-altering changes.

他们热烈的讨论促使莫拉做出了一些微小却能改变生活的变化。

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The take-home message from the JAMA cancer news event is that a cancer diagnosis will be a life-altering event.

《美国医学杂志》关于癌症的新闻事件的关键信息是，癌症诊疗是影响终身的事情。

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But having a child is an irreversible, life-altering decision and you don't find doctors warning women away from that.

但是生育也是一项不可逆转但又改变一生命运的决定，为什么医生们却少有警诫呢？

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PROMO: "This season on 'Who Do You Think You Are?' seven of the world's most beloved celebrities will embark on life-altering journeys into their family history."

VOA: special.2010.06.28

Business is business, and naturally I understand there are times when realities require painful life-altering decisions.

FORBES: Take Care Of Your People And They'll Take Care Of You

The tendency of the powerful to disregard advice has numerous and sometimes life-altering consequences.

FORBES: Bosses Don't Listen: Now There's Proof

Climate panic, after all, is fear of dramatic, life-altering climate changes, not about tenths of a degree.

FORBES: Global Warming: Was It Just A Beautiful Dream After All?