学习记忆等认知功能与海马的密切关系已被众多研究所证实,目前认为长时程增强(long-term potentiation LTP)是海马形成记忆的关键和基础1。临床观察发现,大脑的额叶、颞叶及脑干等部位损伤后,常常遗留有不同程度的学习记忆等障碍。
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The researchers also looked at a molecular correlate of memory called long-term potentiation, or LTP, a mechanism that strengthens connections between neurons.
研究人员同时考察了分子级别与记忆紧密相连的一种机制——长期势差,简称LTP,该机制能够加强神经元之间的联系。
PubMed abstract: Long-term potentiation (LTP) is an enhancement of synaptic strength that can be produced by pairing of presynaptic activity with postsynaptic depolarization.
《公共医学图书馆摘要》:长期电位化(LTP)以前突触活动联对后突触除极化,增加突触讯号强度。
AIM To investigate the effect of acute and chronic lead exposure on CA1 long term potentiation (LTP) and active extracellular signal regulated kinase 2 (ERK2) of rat hippocampus.
目的探讨急、慢性铅中毒对大鼠海马活化的细胞外信号调节激酶2 (ERK2)含量的影响及其与海马CA 1区长时程增强(ltp)的关系。
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