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mammalian target of rapamycin

  • 雷帕霉素哺乳动物靶蛋白:mTOR(雷帕霉素哺乳动物靶蛋白),也称为机械靶蛋白酶,有时被称为FK506结合蛋白12-雷帕霉素相关蛋白1(FRAP1),是一种激酶,在人体中由MTOR基因编码。mTOR是磷脂酰肌醇3激酶相关激酶家族的成员。

网络释义专业释义英英释义

  雷帕霉素靶蛋白

但究竟是形成LAP还是形成LIP,这又取诀于一个分子信号发生器mTOR的活性,是mammalian Target of Rapamycin雷帕霉素靶蛋白)的缩写。雷帕霉素(Rapamycin)是一种可抑制mTOR的药物,但对于免疫系统有非常强的反作用。

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  哺乳动物雷帕霉素靶点

哺乳动物雷帕霉素靶点(Mammalian target of rapamycin, mTOR)是自噬的一个主调控器。有研究表明,在哺乳动物细胞中,mTORCl激酶可能通过调节ULK1复合物的活性来抑制自噬的发生。

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  哺乳动物类雷帕霉素靶蛋白

哺乳动物类雷帕霉素靶蛋白(mammalian target of rapamycin, mTOR)是经过临床验证的肿瘤靶标,但PI3K-AKT-mTOR通路抑制剂是否可用于治疗mTOR基因突变的黑色素瘤患者,目..

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  靶蛋白

哺乳类动物雷帕霉素靶蛋白mammalian target of rapamycin,mTOR)作为一种重要的信号传导分子,参与细胞的多种生理和病理过程,在细胞的生存、生长及增殖过程中起中心调控作...

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短语

mammalian target of rapamycin mTOR 哺乳动物雷帕霉素靶蛋白

p-Mammalian target of rapamycin 磷酸化的哺乳动物雷帕霉素靶蛋白

phosphorylated mammalian target of rapamycin 磷酸化哺乳动物雷帕霉素靶蛋白

mammalian target of the rapamycin 靶蛋白

 更多收起网络短语
  • 哺乳动物雷帕霉素靶蛋白
    哺乳动物雷帕霉素受体
    哺乳类动物的雷帕霉素靶蛋白
    哺乳类雷帕霉素靶蛋白
  • 哺乳动物雷帕霉素靶蛋白

·2,447,543篇论文数据,部分数据来源于NoteExpress

Mammalian target of rapamycin

  • abstract: The mammalian target of rapamycin (mTOR), also known as mechanistic target of rapamycin or FK506 binding protein 12-rapamycin associated protein 1 (FRAP1), is a protein that in humans is encoded by the FRAP1 gene. mTOR is a serine/threonine protein kinase that regulates cell growth, cell proliferation, cell motility, cell survival, protein synthesis, and transcription.

以上来源于: WordNet

权威例句

  • The Novartis drug suppresses a protein called MTOR (mammalian target of rapamycin), which receives incoming growth signals from the surface of the cell and directs them to grow fatter, a necessary step before cell division.

    FORBES: Magazine Article

  • The active ingredient in Rapamune, rapamycin, was discovered decades ago but scientists didn't understand how the drug worked until a graduate student named David Sabatini discovered the mammalian target of rapamycin (mTOR), a protein that acts as part of a complicated set of chemical signals that causes cells to divide.

    FORBES: Magazine Article

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