Problems must first of all be recognized.

首先，必须发现问题。

youdao

We must first of all destroy the enemy's effectives.

我们首先必须消灭敌人的有生力量。

youdao

Reading the reader must first of all sense of style, poetry reading poetry reading methods, reading the novel way of reading the novel.

读者读解首先要有体裁意识，用读诗歌的方法读诗歌，用读小说的方式读小说。

youdao

Best way to lose weight? Well, first of all, you must be active.

减肥最好的办法？嗯，首先，你必须积极主动。

要拥有好身材 - SpeakingMax英语口语达人

"If these chimpanzees are actually motivated by empathy to console victims of aggression, they must first of all be able to recognise that the victim is distressed and then they must know what to do in order to act appropriately to respond to this distress, " said Dr Fraser.

BBC: Hugging benefits fractious chimps

"We thought first of all of the families who must have suffered a serious shock, " he said.

BBC: Murdered pair had bright futures

First of all I must confess, I do trade.

FORBES: The Great Apple Trade?