The frequencies of onset of adverse reactions were generally highest in the first 6 months of treatment and then the frequencies decreased over time or remained stable throughout treatment.
不良反应发生的频率通常在治疗的前6个月最高，然后随着时间降低或在整个治疗中保持稳定。
CONCLUSION the level of IL-18 increases obviously on the 1st day of ACI onset and gradually decreases with the extended course of disease and time of treatment.
结论：白细胞介素18水平在发生急性脑梗死第1天时明显升高，随发病和治疗时间的延长，其水平逐渐下降。
Compare onset time of drug, number of recurrence, and complications after treatment.
治疗后比较两组的药物起效时间、复发人数和并发症发生情况。
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