Orlistat blocks the digestion and absorption of fat in your stomach and intestines.

奥利司他可以在胃及肠道中阻止脂肪的消化与吸收。

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Similarly, the FDA is currently reviewing the safety of orlistat because of reports of serious liver injury in people taking it.

同样的，由于发现服用奥利司他会引起严重的肝损伤，FDA近来正在复核使用奥利司他的安全性。

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Only orlistat (Xenical) has been approved by the FDA for long-term use.

FDA只认可奥利司他(赛尼可)可以长期使用。

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"There is good evidence for the efficacy of Orlistat (Alli) in weight reduction but it should not be used as the sole element of weight management, " says Dr Colin Cable of the Royal Pharmaceutical Society of Great Britain, who reviewed the products.

BBC: Slimming pills: Do the claims add up?

The group said that orlistat, sold in prescription form as Xenical and over-the-counter as Alli, causes serious side effects such as liver injury and kidney failure.

CNN: Why isn't there a safe weight-loss pill?

And that's one theory of the way Orlistat works.

NPR: Slate's Medical Examiner: Xenical OTC