Finally, we also comment on the effect that aggravating conditions, such as oxidative stress and aging, have on the functioning of the autophagic system and its ability to cope with altered proteins.

最后，我们同样论述了氧化应激和老化等影响因素对自噬系统功能的影响和自噬系统处理异常蛋白质的能力。

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Conclusions rat aging might be related with the alteration of oxidative stress status, energy production and protein metabolism.

结论小鼠衰老可能与机体氧化应激状态、能量产生和蛋白质代谢等的改变有关。

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Oxidative stress and damage to all of the major classes of molecules in cells are involved in aging and age-related diseases.

氧化应激和破坏的所有主要类别的分子在细胞参与衰老和与年龄有关的疾病。

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