Pathology: p53 tumor suppressor gene mutation, loss of heterozygosity (LOH) at 11p15 locus. PAX-FKHR gene fusion.
病理学:p53肿瘤抑制基因突变,第11p15基因座杂和性丢失。
They found that the famous tumor suppressor gene, p53, arrested the cell cycle when DADS treatment was present.
他们发现当用DADS治疗时,有名的肿瘤抑制基因p53阻止了细胞循环 。
Some of the mice also had defective versions of the tumor suppressor gene p53, which is mutated in about half of human lung cancers.
一些小鼠还有肿瘤抑制基因p 53缺陷,这种缺陷突变存在与大约一半的人类肺癌。
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