No effects of risperidone on lithium or valproate exposure were observed, despite a 20% increase in valproate peak plasma concentration.
我们没有观察到利培酮合用锂盐或丙戊酸钠的不良反应，尽管在丙戊酸钠上血浆浓度峰值增加20%。
Only recently have the peroral or dermal use been evaluated. Drugs encapsulated into SLN showed a reduced peak plasma concentration and prolonged therapeutic drug level following oral administration.
近年来，SLN的口服和经皮给药逐渐受到重视，研究发现，口服经过SLN包裹后的药物能降低其血药浓度峰值，并延长药物作用时间。
Bioavailability determinations based on the peak plasma concentration can be misleading, because drug elimination begins as soon as the drug enters the bloodstream.
单靠峰时血浆浓度来确定生物利用度会导致误解，因为药物一进入血流就会开始药物消除。
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