Although there was much preclinical interest in the antibiotic geldanamycin as an anti-cancer drug, it turned out to be a poor candidate for clinical trials because of its toxicity.
尽管在临床前试验中抗生素格尔德霉素表现出很强的作为抗癌药物的潜力，但是因为其毒性，这种药物没有能成为具有良好临床试验前景的候选药物。
Preclinical primary safety evaluation result indicates that HQ1127 has a wide safety range, since no toxicity has been observed at the level 50 times of the effective does.
临床前初步安全性评价结果表明，HQ1127安全范围大，在超过有效剂量50倍情况下仍未出现毒副作用。
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